"I am taking a leave of absence to address my health," Smith said through the 49ers. "I am sorry that I have affected my team, my family and the organization. I will do everything in my power to handle this situation the best way possible.Jones was a second or thirdround pick in many drafts, but he started slow this season thanks to a calf injury, frustrating many fantasy owners. The Bengals appear to be the perfect opponent for a back who's hitting his stride. If Jones is on your roster, make sure he's in your lineup this week..

Harbaugh led the Colts to within a desperation heave of the Super Bowl. He got the 49ers into the Super Bowl last season before losing to brother John's Baltimore Ravens. Now, he'd like to win one.SENECA SIGNS OFF: Seneca Wallace, at the bottom of the 49ers depth chart at quarterback, left the team earlier Thursday.Still, Culpepper, who completed 15 of 32 passes for 167 yards, looked very sluggish with his movement and inconsistent